Connect with us

Health

The Chemoprotective Effect of Capsaicin on Prostate Cancer

Can chili pepper help reduce the risk of Prostate Cancer? This independent study has some very interesting results that may shock you.

Published

7 years ago

on

Bowl of bright chili pepper
Photo: The New Medical Journal (NMJ) ®

Primary Study and Abstract written by: Mehmet Erol Yıldırım, Erkan Efe, Ekrem Özyuvalı, Ersin Çimentepe
Independent Study Performed in: 2014/2015, location Turkey.

Is it true that Chili Pepper can assist with lowering the risk of Prostate Cancer? Take a look at this study

Background: Capsaicin is a new and promising anticancer agent with its antagonist effect against multiple carcinogens and mutagens. Capsaicin is widely used all around the world, especially in the southeastern region of Turkey, it is a lifestyle and apart of the food culture. The Turkish chili pepper has a great amount of Capsaicin, thus it can be used in the prevention of Prostate cancer.

It is known that Capsaicin has both effects on the prostate by, diminishing the PSA expression and closing the androgen receptors on the prostate. We tried to evaluate the differences in PSA levels between the people who eat chili pepper regularly or not, in this preliminary study.

Material and Methods: Patients were asked about their daily consumption of Capsaicin and were also admitted to a urology clinic for PSA controls between January-November 2014. Inclusion criteria were being older than 50 years, no history of any prostate disease, urinary tract infection, and drug use (α-blockers, 5 α reductase inhibitors). Also, PSA over 10 ng/dl was excluded from the study.

Participants were divided into two groups; group 1 consisted of participants who eat chili pepper more than one spoon (10 gr) at least 3 days a week and group 2 consisted of participants who do not eat chili pepper. Both groups were statistically analyzed regarding the age and PSA levels.

Results: 827 patients involved in the study whom met the inclusion criteria. There were 476 patients in group 1 and 351 in group 2. As we compared the age of both groups, there was no statistically significant differences between them (60.1±7.3 and 66.7±8.6; respectively p:0.112). When we compared the PSA levels of both groups, the mean PSA of participants who consumed chili pepper was significantly lower than those who don’t eat (1.3±1 and 2.3±1.6; respectively, p<0.05).

Conclusions: Chili Pepper (Capsaicin) is a good candidate for preventing and controlling prostate cancer as it has no side effects and is easy to find.

Additional Sources in relation to the study:

Capsaicin potently suppresses the growth of human prostate carcinoma cells in vitro and in vivo. The antiproliferative activity of capsaicin correlates with oxidative stress induction and apoptosis. Capsaicin also induces ceramide accumulation and endoplasmic reticulum stress in androgen-resistant prostate cells.

Díaz-Laviada I. Effect of capsaicin on prostate cancer cells. Future Oncol. 2010 Oct;6(10):1545-50. doi: 10.2217/fon.10.117. PMID: 21062154.
https://pubmed.ncbi.nlm.nih.gov/21062154/#:~:text=Capsaicin%20potently%20suppresses%20the%20growth,in%20androgen%2Dresistant%20prostate%20cells.

“According to a team of researchers from the Samuel Oschin Comprehensive Cancer Institute at Cedars-Sinai Medical Center, in collaboration with colleagues from UCLA, the pepper component caused human prostate cancer cells to undergo programmed cell death or apoptosis.

Capsaicin induced approximately 80 percent of prostate cancer cells growing in mice to follow the molecular pathways leading to apoptosis. Prostate cancer tumors treated with capsaicin were about one-fifth the size of tumors in non-treated mice.”

Samuel Oschin Comprehensive Cancer Institute at Cedars-Sinai
https://www.cedars-sinai.org/newsroom/pepper-component-hot-enough-to-trigger-suicide-in-prostate-cancer-cells/

Related Topics:
Continue Reading
Click to comment

Leave a Reply

Your email address will not be published. Required fields are marked *

Health

6 Stunning new co-working spaces around the globe

Quis autem vel eum iure reprehenderit qui in ea voluptate velit esse quam nihil molestiae consequatur, vel illum qui.

Published

7 years ago

on

July 20, 2017

By

Photo: Shutterstock

At vero eos et accusamus et iusto odio dignissimos ducimus qui blanditiis praesentium voluptatum deleniti atque corrupti quos dolores et quas molestias excepturi sint occaecati cupiditate non provident, similique sunt in culpa qui officia deserunt mollitia animi, id est laborum et dolorum fuga.

Quis autem vel eum iure reprehenderit qui in ea voluptate velit esse quam nihil molestiae consequatur, vel illum qui dolorem eum fugiat quo voluptas nulla pariatur.

Temporibus autem quibusdam et aut officiis debitis aut rerum necessitatibus saepe eveniet ut et voluptates repudiandae sint et molestiae non recusandae. Itaque earum rerum hic tenetur a sapiente delectus, ut aut reiciendis voluptatibus maiores alias consequatur aut perferendis doloribus asperiores repellat.

Lorem ipsum dolor sit amet, consectetur adipisicing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat.

“Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat”

Nemo enim ipsam voluptatem quia voluptas sit aspernatur aut odit aut fugit, sed quia consequuntur magni dolores eos qui ratione voluptatem sequi nesciunt.

Et harum quidem rerum facilis est et expedita distinctio. Nam libero tempore, cum soluta nobis est eligendi optio cumque nihil impedit quo minus id quod maxime placeat facere possimus, omnis voluptas assumenda est, omnis dolor repellendus.

Nulla pariatur. Excepteur sint occaecat cupidatat non proident, sunt in culpa qui officia deserunt mollit anim id est laborum.

Sed ut perspiciatis unde omnis iste natus error sit voluptatem accusantium doloremque laudantium, totam rem aperiam, eaque ipsa quae ab illo inventore veritatis et quasi architecto beatae vitae dicta sunt explicabo.

Neque porro quisquam est, qui dolorem ipsum quia dolor sit amet, consectetur, adipisci velit, sed quia non numquam eius modi tempora incidunt ut labore et dolore magnam aliquam quaerat voluptatem. Ut enim ad minima veniam, quis nostrum exercitationem ullam corporis suscipit laboriosam, nisi ut aliquid ex ea commodi consequatur.

Continue Reading

Health

3 Ways to make your business presentation more relatable

Nemo enim ipsam voluptatem quia voluptas sit aspernatur aut odit aut fugit, sed quia consequuntur magni dolores.

Published

7 years ago

on

July 18, 2017

By

Photo: Shutterstock
Prev1 of 2
Use your ← → (arrow) keys to browse

Lorem ipsum dolor sit amet, consectetur adipisicing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat.

Nemo enim ipsam voluptatem quia voluptas sit aspernatur aut odit aut fugit, sed quia consequuntur magni dolores eos qui ratione voluptatem sequi nesciunt.

Et harum quidem rerum facilis est et expedita distinctio. Nam libero tempore, cum soluta nobis est eligendi optio cumque nihil impedit quo minus id quod maxime placeat facere possimus, omnis voluptas assumenda est, omnis dolor repellendus.

Nulla pariatur. Excepteur sint occaecat cupidatat non proident, sunt in culpa qui officia deserunt mollit anim id est laborum.

Sed ut perspiciatis unde omnis iste natus error sit voluptatem accusantium doloremque laudantium, totam rem aperiam, eaque ipsa quae ab illo inventore veritatis et quasi architecto beatae vitae dicta sunt explicabo.

“Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat”

Neque porro quisquam est, qui dolorem ipsum quia dolor sit amet, consectetur, adipisci velit, sed quia non numquam eius modi tempora incidunt ut labore et dolore magnam aliquam quaerat voluptatem. Ut enim ad minima veniam, quis nostrum exercitationem ullam corporis suscipit laboriosam, nisi ut aliquid ex ea commodi consequatur.

At vero eos et accusamus et iusto odio dignissimos ducimus qui blanditiis praesentium voluptatum deleniti atque corrupti quos dolores et quas molestias excepturi sint occaecati cupiditate non provident, similique sunt in culpa qui officia deserunt mollitia animi, id est laborum et dolorum fuga.

Prev1 of 2
Use your ← → (arrow) keys to browse

Continue Reading

Health

This is how you dress for a job interview, and land an offer

Sed ut perspiciatis unde omnis iste natus error sit voluptatem accusantium doloremque laudantium, totam rem aperiam.

Published

7 years ago

on

July 12, 2017

By

Photo: Shutterstock

Nulla pariatur. Excepteur sint occaecat cupidatat non proident, sunt in culpa qui officia deserunt mollit anim id est laborum.

Sed ut perspiciatis unde omnis iste natus error sit voluptatem accusantium doloremque laudantium, totam rem aperiam, eaque ipsa quae ab illo inventore veritatis et quasi architecto beatae vitae dicta sunt explicabo.

Neque porro quisquam est, qui dolorem ipsum quia dolor sit amet, consectetur, adipisci velit, sed quia non numquam eius modi tempora incidunt ut labore et dolore magnam aliquam quaerat voluptatem. Ut enim ad minima veniam, quis nostrum exercitationem ullam corporis suscipit laboriosam, nisi ut aliquid ex ea commodi consequatur.

At vero eos et accusamus et iusto odio dignissimos ducimus qui blanditiis praesentium voluptatum deleniti atque corrupti quos dolores et quas molestias excepturi sint occaecati cupiditate non provident, similique sunt in culpa qui officia deserunt mollitia animi, id est laborum et dolorum fuga.

Quis autem vel eum iure reprehenderit qui in ea voluptate velit esse quam nihil molestiae consequatur, vel illum qui dolorem eum fugiat quo voluptas nulla pariatur.

Temporibus autem quibusdam et aut officiis debitis aut rerum necessitatibus saepe eveniet ut et voluptates repudiandae sint et molestiae non recusandae. Itaque earum rerum hic tenetur a sapiente delectus, ut aut reiciendis voluptatibus maiores alias consequatur aut perferendis doloribus asperiores repellat.

Lorem ipsum dolor sit amet, consectetur adipisicing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat.

“Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat”

Nemo enim ipsam voluptatem quia voluptas sit aspernatur aut odit aut fugit, sed quia consequuntur magni dolores eos qui ratione voluptatem sequi nesciunt.

Et harum quidem rerum facilis est et expedita distinctio. Nam libero tempore, cum soluta nobis est eligendi optio cumque nihil impedit quo minus id quod maxime placeat facere possimus, omnis voluptas assumenda est, omnis dolor repellendus.

Continue Reading

Trending

The New Medical Journal (NMJ) ® content is for research, educational and informational purposes only. Our website, content, and products are not intended to be a substitute for professional medical assistance, advice, diagnosis, and/or treatment. See additional information.
Copyright © 2022 The New Medical Journal - All rights reserved.